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Duratia 60 mg is a medication primarily used for the treatment of premature ***** in men. It contains dapoxetine hydrochloride as its active ingredient, which is a selective serotonin reuptake inhibitor (SSRI) specifically designed to delay *****.

When considering potential negative interactions with Duratia 60 mg, it's important to focus on medications that may affect serotonin levels or have similar mechanisms of action. Here are some categories of medications that may interact negatively with Duratia 60 mg:

Other SSRIs or SNRIs: Combining Duratia 60 mg with other selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs) may increase the risk of serotonin syndrome, a potentially life-threatening condition characterized by symptoms such as agitation, confusion, rapid heart rate, and high blood pressure.
Monoamine Oxidase Inhibitors (MAOIs): MAOIs are another class of antidepressant medications that can increase serotonin levels. Combining Duratia 60 mg with MAOIs may also increase the risk of serotonin syndrome. MAOIs should be discontinued at least 14 days before starting Duratia 60 mg.
Tricyclic Antidepressants (TCAs): TCAs are older antidepressant medications that can also affect serotonin levels. Combining Duratia 60 mg with TCAs may increase the risk of serotonin syndrome or other adverse effects.
Serotonergic Medications: Other medications that increase serotonin levels, such as certain migraine medications (e.g., triptans), opioid pain medications (e.g., tramadol), and certain herbal supplements (e.g., St. John's wort), may interact negatively with Duratia 60 mg and increase the risk of serotonin syndrome.
Medications Metabolized by CYP3A4: Duratia 60 mg is metabolized primarily by the cytochrome P450 enzyme CYP3A4. Medications that inhibit or induce CYP3A4 activity may affect the metabolism of Duratia 60 mg and alter its effectiveness or increase the risk of side effects.
It's crucial to discuss all medications (including prescription, over-the-counter, and herbal supplements) with your healthcare provider before starting Duratia 60 mg to identify potential interactions and ensure safe use. Your doctor can provide personalized recommendations and guidance based on your individual health status and medication regimen. If you experience any concerning symptoms while taking Duratia 60 mg, such as dizziness, nausea, or changes in mood, contact your healthcare provider promptly for further evaluation and management.

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